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Phanish MK, Wahab NA  Hendry BM , Dockrell MEC (2005)

 TGF-b1-Induced Connective Tissue Growth Factor (CCN2) Expression in Human Renal Proximal Tubule Epithelial cell Requires Ras/MEK/ERK and Smad Signalling

Nephron Exp Nephrol. 2005;100(4):e156-65.

 

 Khwaja A, Dockrell MEC, Hendry BM Sharpe CC (2006)

Prenylation is not necessary for endogenous Ras activation in non-malignant cells

 J Cell Biochem. Feb 1;97(2):412-22.

 

Phanish ML, Wahab NA, Colville-Nash P, Hendry BM, Dockrell MEC  (2006)

The differential role of Smad2 and Smad3 in regulation of pro-fibrotic TGFb1 responses in human proximal tubule epithelial cells Biochem J. 15;393(Pt 2):601-7

 

Niculescu-Duvaz I, D'Mello L, Maan Z, Barron JL, Newman DJ, Dockrell MEC, Kwan JTC (2006) Development of an outpatient finger-prick glomerular filtration rate procedure suitable for epidemiological studies. Kidney Int 69(7):1272-5

                                                       

Diwakar R, de C Pearson A, Colville-Nash P, Brunskill NJ, Dockrell MEC (2007) The Role Played by Endocytosis in Albumin Induced Secretion of TGFβ-1 by Proximal Tubular Epithelial Cells  Am J Physiol Renal Physiol. 2007 May;292(5):F1464-70. Epub  Jan 9.

 

Niculescu-Duvaz I, Phanish MK, Colville-Nash P, Dockrell ME. (2007) The TGFbeta1-induced fibronectin in human renal proximal tubular epithelial cells is p38 MAP kinase dependent and Smad independent. Nephron Exp Nephrol.;105(4):e108-16. Epub 2007 Mar 7.

 

Mafham MM, Niculescu-Duvaz I, Barron J, Emberson JR, Dockrell ME, Landray MJ, Baigent C. (2007 ) A Practical Method of Measuring Glomerular Filtration Rate by Iohexol Clearance Using Dried Capillary Blood Spots. Nephron Clin Pract. May 22;106(3):c104-c112

 

Diwakar R, de C Pearson A, Colville-Nash P, Baines DL, Dockrell MEC (2008) Role played by Disabled 2 in albumin-induced MAP kinase signalling Biochem Biophys Res Commun  Feb 15;366(3):675-80. Epub 2007 Dec 10.

 

Motazed R, Colville-Nash P, Kwan JTC, Dockrell MEC (2008) BMP-7 and Proximal Epithelial Cells: activation of multiple signaling pathways reveals a novel anti-fibrotic mechanism Pharm Res. 2008 Oct;25(10):2440-6

 

Pearson A, Kwan  JT, Colville-Nash P, Dockrell ME (2008) Albumin induces IL-6 from primary human proximal tubular epithelial cells J Nephrol. Nov-Dec;21(6):887-93.

 

Browne JA, Pearson AL, Zahr RA, Niculescu-Duvaz I, Baines DL, Dockrell ME. (2008) TGF-beta activates ERK5 in human renal epithelial cells. Biochem Biophys Res Commun. Aug 29;373(3):

 

Roderick P, Lightstone L, Harris S, Lapsley M, Dockrell M, Lim E, Chambers J, Kooner JS (2009)

Diabetes plus: Prevalence of chronic kidney disease in South Asian and Black minorities: findings from a population based screening study in London, UK

J Epidemiol Community Health 2009;63:Suppl 2 64 

 

Dockrell ME, Phanish MK Hendry BM (2009)

TGF-beta auto-induction and Connective Tissue Growth Factor expression in human renal epithelial cells requires N-Ras  Nephron . 112(3):e71-9.

 

Baines, D, Ly L, Gambling L, Woolhead A, Hazell M, Dockrell ME (2009) Lipopolysaccharide modifies amiloride-sensitive Na+ transport processes across human airway cells: role of mitogen activated protein kinases ERK 1, 2 and 5. Pflugers Arch. 2010 Feb;459(3):451-63.

 

Veerasamy M , Nguyen Tri, Motazed R Pearson A, Goldschmeding R, Dockrell M (2009)  Differential regulation of E-cadherin and α;-Smooth Muscle Actin by BMP 7 in human renal proximal tubule epithelial cells and its implication in renal fibrosis Am J Physiol Renal Physiol. 2009 Nov;297(5):F1238-48. Epub 2009 Sep 9.

 

Browne NK, Huang Z, Dockrell M, Hashmi P, Price RG.(2010) Evaluation of new chromogenic substrates for the detection of coliforms Appl Microbiol. 2010 May;108(5):1828-38.

 

 Phanish MK, Winn S, Dockrell ME (2010) Connective Tissue Growth Factor-(CTGF, CCN2) - a marker, mediator and therapeutic target for renal fibrosis Nephron (Review) Nephron Exp Nephrol. 2010;114(3):e83-92.

 

Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Smith GD, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, et al. (2010)

Genetic loci influencing kidney function and chronic kidney disease.

Nat Genet. 2010 May;42(5):373-5.

 

Lawson CS, Campbell KL, Dimakopoulos I, Dockrell ME (2012) Assessing the Validity and Reliability of the MUST and MST Nutrition Screening Tools in Renal Inpatients J Ren Nutr. 2012 Sep;22(5):499-506.

 

Veerasmay M, Panish MK, Dockrell ME (2013) Smad mediated regulation of Inhibitor of DNA binding 2 and its role in phenotypic maintenance of human renal proximal tubule epithelial cells  PLoS One. 2013;8(1):e51842

              

Badshah II, Baines DL, Dockrell ME.(2014)

Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes.

Front Pharmacol. 2014 Apr 21;5:71

 

Dockrell ME

Erk5 – a double edged sword in the fight against diabetic nephropathy

Treatment Strategies in Diabetes 2014

 

Phanish MK, Heidebrecht F, Nabi ME, Shah N, Niculescu-Duvaz I, Dockrell ME.

The Regulation of TGFβ1 Induced Fibronectin EDA Exon Alternative Splicing in Human Renal Proximal Tubule Epithelial Cells.

J Cell Physiol. 2015 Feb;230(2):286-95.

 

Yates S, Lapsley M, Phanish MK, Dockrell MEC

  K-cadherin; a novel marker of progression in diabetic renal disease

Nephrology Dialysis Transplantation, May 2015 Volume 30, Issue suppl_3, 1, Pages iii145,

 

 Lane K, Dixon JJ, MacPhee IAM, Philips BJ, Dockrell M

Hepatocellular response to acute kidney injury in the critically ill: serum induces CYP2D6 transcription Intensive Care Med Exp. 2015 December; 3(Suppl 1): A627.

 

Madne. TH, Dockrell MEC CCN3, a key matricellular protein, distinctly inhibits TGFβ1-mediated Smad1/5/8 signalling in human podocyte culture Cell Mol Biol 2018  64 (3) 5-10

 

Madne. TH, Dockrell MEC  Human podocytes responses to alternatively spliced Extra domain A Fibronectin in Culture Cell Mol Biol  2018  64 (3) 45-52

 

Madne. TH, Dockrell MEC   TGFβ1-mediated expression and alternative splicing of Fibronectin Extra Domain A in human podocyte culture  Cell Mol Biol  2018  64 (3)  17-24

 

Madne TH, Dockrell MEC. TGFβ1-mediated PI3K/Akt and p38 MAP kinase dependent alternative splicing of fibronectin extra domain A in human podocyte culture. Cell Mol Biol. 2018 Apr 30;64(5):127-135.

 

Madne TH, Dockrell MEC.

Human podocytes responses to alternatively spliced Extra domain A Fibronectin in

culture.

Cell Mol Biol. 2018 Feb 28;64(3):45-52

 

Madne TH, Dockrell MEC.

TGFβ1-mediated PI3K/Akt and p38 MAP kinase dependent alternative splicing of fibronectin extra domain A in human podocyte culture.

Cell Mol Biol. 2018 Apr 30;64(5):127-135.

 

 Kalsi KK, Garnett JP, Patkee W, Weekes A, Dockrell ME, Baker EH, Baines DL.

Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ-mediated phosphorylation of occludin.

J Cell Mol Med. 2019 Jan;23(1):317-327.

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Salota R, Lapsley M, Nabi E, Packer S, Hyer S, Dockrell M

Time-resolved fluorescence immunoassay for urine retinol-binding protein is more sensitive than polyclonal and monoclonal assays.

.Ann Clin Biochem. 2021 Jun 12:45632211020034. doi: 10.1177/00045632211020034.

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Pan X, Phanish MK, Baines DL, Dockrell MEC

High glucose-induced Smad3 linker phosphorylation and CCN2 expression are inhibited by dapagliflozin in a diabetic tubule epithelial cell model.

Biosci Rep. 2021 Jun 25;41(6):BSR20203947. doi: 10.1042/BSR20203947

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Phanish MK, Chapman AN, Yates S, Price R, Hendry BM, Roderick PJ, Dockrell MEC

Evaluation of Urinary Biomarkers of Proximal Tubular Injury, Inflammation, and Fibrosis in Patients With Albuminuric and Non-albuminuric Diabetic Kidney Disease.

.Kidney Int Rep. 2021 Feb 2;6(5):1355-1367. doi: 10.1016/j.ekir.2021.01.012. eCollection 2021 May.PMID: 34013114

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